Vol. 6, Issue 1, Part A (2024)

Aims: To determine the maternal and perinatal outcome among pregnant woman with DLFT.
Materials and Methods: A prospective study was conducted in the Department of Obstetrics and Gynaecology, Tertiary care institute in West Bengal ESI-PGIMSR JOKA over a period of one year (January to December 2023). All pregnant woman with DLFT were included in the study.
Results and Analysis: Incidence of DLFT in our hospital was 4.88%, among 1923 deliveries, 94 were diagnosed to have deranged liver function out of which 90.4% were obstetric cholestasis, 6.38% severe pre-eclampsia, 2.12% Hepatitis B, 1.06% leptospira. 71.2% were primigravida, Gestational Diabetes Mellitus associated in 28.7%, Gestational hypertension in pregnancy in 15.9% and few with hypothyroidism, Bronchial asthma. Most of the patients were delivered by cesarean section for various reasons, 26.5% were preterm, 20 admitted to NICU.
Conclusion: Early diagnosis and management is necessary to decrease maternal and perinatal mortality and morbidity.